Action and mechanism
A local anesthetic of the amide type. Lidocaine blocks voltage-gated na channels, decreasing the rate of neuronal depolarization and the conduction velocity of the nerve impulse. The blockade is reversible, and once the concentration falls below a minimum threshold, the nerve fully recovers its function.
The blocking effect is not accompanied by alterations in the resting potential or repolarization.
The anesthetic effects appear rapidly, in about 3-5 minutes, and last for about 1.5 Hours. Special warnings
The minimum doses that eliminate symptoms should always be used to avoid the risk of systemic effects.
Monitoring:
* Cardiac function, including ecg monitoring, in people with severe cardiovascular disease. Seniors no specific problems have been described in the elderly that would require a dosage adjustment. Patient advice
Use the dose recommended by your doctor.
Do not apply lidocaine to mucous membranes, including the eyes, or to irritated, inflamed, or broken skin. In case of contact with the eyes, immediately rinse them with lukewarm water or saline solution and protect them until sensitivity returns.
Before starting treatment, you should inform your doctor if you have previously suffered or are currently suffering from:
* Severe liver diseases.
* Serious heart conditions, including cardiac arrhythmias.
Inform your doctor if you are being treated with:
* Antiarrhythmic medications.
* Medications for myocardial infarction, such as ni...
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