Action and mechanism a non-steroidal anti-inflammatory drug nsaid belonging to the arylpropionic group, which acts by preventing the synthesis of prostaglandins through the competitive and reversible inhibition of cyclooxygenase activity, the enzyme that converts arachidonic acid into prostaglandins. It has been shown to be slightly more effective than naproxen, but with a slightly higher incidence of gastrointestinal adverse effects than ibuprofen. Seniors elderly patients are at greater risk of serious adverse reactions. If an nsaid is deemed necessary, the lowest effective dose should be administered for the shortest possible duration. Patients should be regularly monitored for gastrointestinal bleeding during treatment. Contraindications
Known hypersensitivity to flurbiprofen or nsaid allergy .
Patients with a history of hypersensitivity to acetylsalicylic acid or other nsaids, which includes patients who have experienced asthma attacks, acute rhinitis, urticaria or angioneurotic edema after using acetylsalicylic acid or other nsaids.
Digestive hemorrhage , esophagus hemorrhage , active peptica ulcera , cerebral hemorrhage .
Severe kidney failure.
Severe liver failure. Pregnancy fda pregnancy category b, fda pregnancy category d in the third trimester. There are no adequate and well-controlled studies in humans. Occasional use, except shortly before delivery, does not appear to produce adverse fetal effects. However, with chronic use during the third trimest...
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Action and mechanism a non-steroidal anti-inflammatory drug nsaid belonging to the arylpropionic group, which acts by preventing the synthesis of prostaglandins through the competitive and
